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Each brick only weighed 3 kilos buy orlistat online now weight loss pills venom hyperdrive 30, but they were lifted in bundles of eight order 60mg orlistat with amex weight loss pills bee pollen, weighing a total of 24 kilos purchase orlistat 120 mg with visa weight loss programs that work. Every day, furthermore, he had quite a few 40-kilo lifts, amounting to 1-2 tonnes per week. The bricklayers assistant had hip-loading work for much more than 15 years, with a daily load of 6-9 tonnes. There were also many heavy single lifts of more than 20 kilos, amounting to more than 1 tonne per week. As the total exposure period was very long (more than 20 years) and the work furthermore involved a number of very heavy single lifts of more than 40 kilos, the daily load requirement can be reduced, in this case, to a minimum of 6 tonnes. The daily work with a heavily loaded wheelbarrow, which involved many heavy, partial lifts and starts, is also included as a special load factor. Also, there is good time correlation between the heavy, hip-loading lifting work and the onset of the disease after many years exposure. Example 5: Recognition of bilateral degenerative arthritis (stone paving worker) A 56-year-old man worked for a local authority for 28 years as a stone paving worker. About half the working time he laid cobblestone drives, about one third of the time he laid highroad stone drives and other drives, and the remaining part of the working time he laid pavements. Tiles and stones weighed from 10-20 kilos up to 60-80 kilos and were typically laid manually. Kerbstones weighed up to 100-200 kilos and were handled and lifted by two men at a time. The work was performed in very hip-loading, stooping postures and also involved much twisting of the hip joints. There were many, very heavy single lifts of 40 kilos or more, equivalent to several tonnes a week. About 18 years after commencing the work he had moderate 99 symptoms with hip joint pain. However, he only saw a doctor several years later and was diagnosed with moderate to severe degenerative arthritis of both hip joints. The paving worker had heavy, hip-loading work for much more than 15 years and a daily lifting load of 6-7 tonnes. There is also good time correlation between the work and the onset of the disease after 18 years. Example 6: Recognition of bilateral degenerative arthritis (dray man/beer delivery man) In x-ray examinations a 49-year-old man was diagnosed with severe degenerative arthritis of the right hip joint and slight to moderate degenerative arthritis of the left hip joint. By the time he was diagnosed, he had worked as a dray man/beer delivery man for 12 years. His work consisted in delivering cases of beer and soda to shops, restaurants, pubs, etc. The last couple of years the lorry was loaded with a pallet lifter without any manual lifts, but the dray man practically always had to deliver manually the cases of beer and soda on the customers premises. The daily lifting load the first years was in excess of 12 tonnes, and the last couple of years it was 8-10 tonnes. The single lifts weighed between 17 kilos (one case of soda) and 45 kilos (two cases of beer lifted at the same time). Besides, he had many heavy single lifts of at least 20 kilos (one case of beer weighs 22-23 kilos), equivalent to more than 1 tonne per week. Finally he had several, very heavy, single lifts of at least 40 kilos (two cases of beer together), which were made under particularly stressful lifting conditions. Example 7: Claim turned down unilateral degenerative hip arthritis after moderate lifting work (river supervisor) A 56-year-old man worked for 23 years as a river supervisor for a regional authority. The work mainly consisted in dredging of rivers and looking after the river banks, including grass mowing and nature conservation. The daily lifting load was about 5-6 tonnes, with typical single lifts of 10-12 kilos, in the form of wet river material on a fork. The lifting conditions were usually difficult he stood in the river, shovelling the river material upwards onto the river bank. Towards the end of the period the river supervisor was diagnosed with moderate to severe degenerative arthritis of the right hip, whereas x-rays of the left hip showed normal conditions. The river supervisor did not suffer from bilateral degenerative hip arthritis, which is a requirement for recognition on the basis of the list. And even if the degenerative arthritis had been bilateral, it still would not qualify for recognition on the basis of the list as the work did not involve sufficient hip-loading lifting work. Besides, there were no heavy single lifts of at least 20 kilos, amounting to a total of at least 1 tonne per week. Nor did the river supervisor have many 100 daily, very heavy single lifts of at least 40 kilos or other special stress conditions that might give grounds for reducing to 5-6 tonnes the daily requirement for a lifting load of 8 tonnes. In this case there are no grounds for submitting the claim to the Occupational Diseases Committee as the river supervisor did not perform heavy, hip-loading work, which is a special risk factor in connection with the development of unilateral degenerative hip arthritis. Example 8: Claim turned down bilateral degenerative hip arthritis after lifting work in good lifting postures (fitting worker/controller) A 57-year-old woman was diagnosed by a medical specialist and after x-ray examinations with moderate, degenerative arthritis of both hips. She had worked for about 16 years in a business that manufactured components for the machine industry. Her work consisted in controlling fittings of components lying on a conveyor belt in front of her, and in occasionally checking with a screwdriver the correct fitting of individual components. The work was performed in a standing posture in front of the belt, and each object typically weighed between 5 and 8 kilos. When performing the control, the fitting worker lifted each single object in order to assure its quality and then put it back on the belt in front of her. The daily lifting load amounted to approximately 8 tonnes in the form of approximately 1,000-1,500 lifted components per day. To this should be added a number of daily lifts of boxes with discarded metal objects and pallets weighing 20-30 kilos each and constituting an aggregate weekly load of about 1 tonne. The heavy single lifts amounting to about 1 tonne per week were made in hip- loading lifting postures. The fitting worker for 16 years performed lifting work equivalent to about 8 tonnes, with typical single lifts of 5-8 kilos. From a general point of view, the total daily lifting load of 8 tonnes and the duration of the load for more than 15 years meet the requirements of the list. By far the most lifts were performed in good lifting postures, however, which were not particularly stressful for the hip joints. Even though the injured person met the general requirements to the daily load and the duration of the load as well as the requirement for heavy single lifts amounting to at least 1 tonne per week, the work cannot, since the lifting conditions in connection with the other lifted objects were not stressful for the hip joints, be deemed to be sufficiently stressful for the development of bilateral degenerative hip arthritis. Influence of work with heavy lifting, climbing stairs or ladders, or combining kneeling/squatting with heavy lifting. It is an aseptic bone necrosis (aseptic = infectious condition without bacteria, necrosis = tissue death) of the epiphysus of the caput femoris (caput = head, femur = thigh bone, epiphysiolysis = slipped growth area).
Seasonal changes were most pronounced in the testes buy discount orlistat 120mg weight loss pills johnson city tn, with a maximum and minimum volume of 2 order orlistat cheap online weight loss quick. These fndings are in agreement with our recent results on steroid hormone metabolite concentrations measured in faeces and urine (Jewgenow et al buy cheap orlistat 60 mg weight loss pills consumer reports. To our knowledge, the existence of elevated progesterone during lactation and presumably active corpora lutea throughout much of the year is unique for felid species. The existence of large corpora lutea and increased volume of luteal tissue several months after parturition detected by ultrasound examination (Table 1) allows us to assume that progesterone is of luteal origin, although additional studies are required to confrm that the source is ovarian and not adrenal. The low but steady progesterone concentration may function to induce a negative feed back to inactivate folliculogenesis. That would represent a mechanism to turn the normally polyoestric cycle seen in most felids into in a monoestric cycle in the lynx and thus contribute to the seasonality of its breeding pattern so as to match the seasonal sperm production in the males (Gritz et al. The apparent correlation between estrogen and progesterone secretion suggested by current results may refect the important role of estrogens, which might help maintain progesterone receptors and sensitivity for progesterone. Qu e v e d o a n d kata r I n a Je w g e n o w sPecIes age class Recent bReedIng mean (sd) mean (sd) no. Whether this is caused by absence of fertilization of oocytes after ovulation or by early embryonic resorption or possibly by lutenization of antral follicles and subsequent development of accessory corpora lutea is yet uncertain. Our comparative approach is very useful to gain new insights into the reproductive pecularities of both Eurasian and Iberian lynx. Since frequent examination procedures are not possible in the endangered Iberian lynx, the Eurasian lynx can serve as a model species. Assessment of reproductive health by transrectal ultrasound was applied to study seasonal changes in male and female Eurasian lynx. This knowledge was essential to assess the reproductive soundness and physiology of the Iberian lynx. The ultrasonographical fndings strongly suggest that corpora lutea developed from ovulations in mid-winter and stayed active until at least late november. Their functional role on lynx reproduction is still unknown, but we hypothesize that the associated elevated progesterone may support lactation, prevent a new estrus cycle and thus restrict the breeding season to midwinter (as opposed to the strategy used by the polyoestric bobcat). Further comparative longitudinal ultrasound and hormone evaluations on all species within the lynx family are needed to further elucidate their unique reproductive patterns. Pregnancy diagnosis in urine Diagnostic and treatment of reproductive disorders in wild of Iberian lynx (Lynx pardinus). Reproduction in Domestic Animals 43 (2) 74- Asdells Patterns of Mammalian Reproduction. General and ultrasonographic examination of the female urogenital comparative Endocrinology 149, 151-158. Seasonal profles of ovarian activity in Iberian lynx (Lynx pardinus) based on urinary hormone metabolite analyses. Reproductive health assessment of captive pure-bred Amur leopards (Panthera pardus Jewgenow, K. Qu e v e d o a n d kata r I n a Je w g e n o w on urinary hormones, in: Vargas, A. Application to in situ and ex situ conservation, Iberian Lynx Ex situ conservation seminar series: Book of Proceedings. Disease of captive cheetahs (Acinonyx jubatus): results of the cheetah research council pathology Tsutsui, T. It takes two days to learn everything about a man; to know animals you will need more time. Para llevar a cabo con xito el Programa de cra en cautividad es necesario disponer de sistemas de diagnstico de gestacin fables y no invasivos. Durante tres aos de estudio, se tomaron muestras de orina de seis hembras de lince ibrico en cautividad (un ciclo sin gestacin, un ciclo de pseudogestacin y 11 ciclos de gestacin). Adems, se utiliz el test comercial Witness Relaxin para detectar la presencia de la hormona relaxina en orina, as como en muestras de sangre obtenida mediante chinches hematfagos. En el lince ibrico el perfl de la progesterona en orina no mostr el patrn habitual de aumento durante la gestacin que se observa generalmente en otras especies de felinos. Sin embargo, s se observ un incremento de estrgenos en orina, que aumentaron de 3. Los niveles de estrgenos fueron ms elevados en las hembras gestantes que en las que presentaban pseudogestacin (P<0. En una hembra que no copul no se observ ninguna diferencia en los niveles de estrgenos entre la estacin reproductiva y la no reproductiva. Aunque el test WitnessRelaxin fue positivo en muestras de plasma obtenidas mediante chinches hematfagos a partir de hembras entre los 32 y 56 das de gestacin, la prueba no funcion en muestras de orina obtenidas durante el mismo intervalo de tiempo. Tras concentrar la orina por ultrafwiltracin (>50 x), se observ una leve reaccin en el test WitnessRelaxin en muestras obtenidas entre los 29 y los 46 das de gestacin. En muestras de orina concentrada obtenidas a partir de hembras no embarazadas y de hembras al inicio de la gestacin los resultados de la relaxina fueron negativos. Sin embargo, se debe juzgar con precaucin cualquier resultado negativo en la prueba de relaxina, dado que los niveles de esta hormona podran situarse por debajo del umbral de deteccin del test. Successful Captive Breeding demands reliable methods for monitoring reproduction, including reliable non-invasive pregnancy diagnosis. During a three year study, urine samples from six captive Iberian lynx females were obtained (1 non-pregnant, 1 pseudo-pregnant and 11 pregnant cycles). Additionally, the Witness Relaxin test was used to determine relaxin in urine samples and blood plasma collected by blood suckling bugs. Urinary progesterone did not follow the typical pregnancy-related course of felids. In the Iberian lynx we failed to demonstrate a progesterone elevation during pregnancy. A comparison of pseudo-pregnant with pregnant cycles revealed a further increase of estrogens caused by implantation (P<0. In one female that failed to mate, no difference was detected between estrogen levels during breeding and non-breeding season. Although the WitnessRelaxin test was positive in plasma samples collected from animals between days 32-56 of pregnancy, it failed to detect relaxin in urine samples collected from the same stage of pregnancy. A weak relaxin reaction in urine samples collected from animals between days 29-46 of pregnancy was detectable after urines were concentrated by ultrafltration (>50 x). Concentrated samples obtained from non-pregnant and early pregnant animals yielded negative test results. In conclusion, urinary estrogens and the Witness Relaxin test can be applied for pregnancy diagnosis in the Iberian lynx. A negative relaxin test, however, must be judged carefully because hormone levels might be below the detection level. Besides ensuring the existence of the Iberian lynx in captivity, the Ex situ Programme has the beneft of allowing the study of various aspects of the species biology and physiology that could not easily be studied in the wild. One of such aspects is the understanding of reproductive physiology and the development of methods for non-invasive monitoring of the reproductive status (Braun et al. Pregnancy diagnosis by monitoring ovarian physiology is of particular importance in this respect, particularly as a management tool for the captive Breeding Programme. In lynx, however, fecal steroids T do not follow the typical pregnancy pattern of felids (Brown et al.
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