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Other techniques purchase generic mycelex-g from india antifungal nappy cream, such as functional magnetic reso- nance imaging buy mycelex-g cheap yates anti fungal, multi channel electroencephalography and magnetoen- cephalography have all attracted more attention generic mycelex-g 100mg mastercard fungus gnats diseases. They are in themselves exciting developments and we have learned much about the human brain from them. However, they all record brain activity in one form or another and thus cannot reveal how the brain would function in the absence of a Reverse engineering the human mind 181 certain component. Magnetic stimulation offers a unique combination of component removal and timing and for these reasons has a special role in addressing psychological problems. So prediction 1 is that every Psychology Department in the world will have a magnetic stimulation lab. My second prediction concerns the ability of magnetic stimulation to inﬂuence cortical activity. Already we are seeing signs it may be able to replace electroconvulsive therapy in the treatment of depression and one can only hope for an acceleration in the development of this program. In addition there is potential for magnetic stimulation to be used to inﬂuence the progress of those recovering from stroke, if the ability to inﬂuence learning turns out to have real potential. In these kinds of cases magnetic stimulation plays the role of treatment and tester because one can chart progress by interfering with functions as well trying to enhance them. My ﬁnal prediction is that magnetic stimulation will be used in conjunction with the other imaging techniques to obtain a picture of the brain in action when it has been used to either impede or enhance processing. Using PET (Positron Emission Tomography) scanning Tomas Paus in Montreal measured changes in cere- bral blood ﬂow after subjects had received magnetic stimulation. The pattern of brain activation was not random: the areas activated by mag- netic pulses included the site beneath the stimulating coil and several regions to which that area was anatomically connected. From hereon mag- netic stimulation will be used to assess which of those activations have a functional meaning by applying it and recording brain blood ﬂow when subjects are performing a task. It may even lead to crossing one of the longest bridges in cognitive neuroscience: how do the functionally special- ised regions of the brain act together to produce our experience of the world? The upshot of all this will be what science always aims for – counterintuitive insights into a piece of the natural world. Whatever happens there is only one route scientists can take and for a reminder we can go back to Faraday. In 1859, while trying to devise a means of measuring gravitational forces, he wrote in his diary, ‘Let the imagina- tion go, guiding it by judgement and principle, but holding it in and direct- ing it by experiment’ – good advice for the next millennium of science. Thompson Michael Thompson was born in Cottingham, Yorkshire, on 7 June 1937, studied at Cambridge, where he graduated with ﬁrst class honours in Mechanical Sciences in 1958 and obtained his PhD in 1962 and his ScD in 1977. He was a Fulbright researcher in aeronautics at Stanford University and joined University College London (UCL) in 1964. He has published four books on instabilities, bifurcations, catastrophe theory and chaos and 183 184 CONTRIBUTOR BIOGRAPHIES was appointed professor at UCL in 1977. Michael was elected a fellow of the Royal Society in 1985 and was awarded the Ewing Medal of the Institution of Civil Engineers. In 1991 he was appointed director of the Centre for Nonlinear Dynamics at UCL. He is currently editor of the Royal Society’s Philosophical Transactions (Series A) which is the world’s longest running scientiﬁc journal. His scientiﬁc interests include nonlinear dynamics and their applications. His recreations include walking, tennis and astronomy with his grandson Ben, shown above. Roberts Gareth Roberts’ research interests are centred on the quantum dynamics of ultrafast laser–molecule interactions and molecular collisions. He was brought up in South Wales and holds degrees from the Universities of London and Cambridge. His interest in ultrafast phenomena was triggered in 1989 by an inspirational stay as a NATO Postdoctoral Fellow in the laboratory of Professor A. He is 36 years old and is currently a Royal Society University Research Fellow at Cambridge University and a Fellow of Churchill College, Cambridge. Sutcli≈e Born in Rochdale, Lancashire, Michael Sutcliffe (left) studied at Bristol, where he graduated with ﬁrst class honours in chemical physics in 1985, and at Birkbeck College, London, where he obtained his PhD in protein modelling in 1988. Aged 35, he was a SERC/NATO Fellow at Oxford University and Junior Research Fellow at Linacre College, a Royal Society University Fellow at Leicester University, and joined Leicester University as a Lecturer in 1998, where he is currently Reader. His research involves the development and use of computational methods to address one of the major challenges in the biomolecular sciences, understanding the relation- ship between protein structure and function. He has over 60 publications, including specialised reviews, and was elected a Fellow of the Royal Society of Chemistry in 1999. He graduated from King’s College, London, with ﬁrst class honours in 1985 and was awarded the Sir William Robson prize. In 1988, he was elected a Research 186 CONTRIBUTOR BIOGRAPHIES Fellow at St John’s College and was awarded the Humphreys Research prize. At Cambridge, Nigel was a Research Fellow of the Royal Commission for the Exhibition of 1851 and Royal Society University Research Fellow. Aged 36, Nigel is now Professor at Leicester University and Lister Institute Research Fellow. His scientiﬁc interests include mechan- istic and quantum enzymology: his recreational interests include Victorian and College philately. Goodman Jonathan Goodman studied chemistry at Cambridge, graduating with a BA in 1986, and with a PhD in organic chemistry in 1990. He then worked at Columbia University, New York, with Professor Clark Still, before return- ing to Cambridge as a Research Fellow at Clare College. He is now a Royal Society University Research Fellow in the Department of Chemistry, and uses both computational and experimental techniques to study organic chemistry. He is aged 35, and has recently published a book with the Royal Society of Chemistry, Chemical Applications of Molecular Modelling, which introduces experimental organic chemists to computational tech- niques. Macquarrie Born in Oban, Argyll, in 1960, Duncan Macquarrie studied Pure and Applied Chemistry at the University of Strathclyde, graduating with a ﬁrst class degree in 1982 and a PhD in 1985. He then moved to York, where he carried out research in Phase Transfer Catalysis. He subsequently spent time in industry, where he worked in the UK and abroad, mostly in syn- thetic chemistry, but always with an interest in method development and catalysis. He returned to York in 1995 to take up a Royal Society University Research Fellowship, and has developed a range of novel cata- lysts for green chemistry. He is Associate Editor of Green Chemistry, and a National Member of Council with the Royal Society of Chemistry. He went on to study at Bristol University, where he graduated with a ﬁrst class honours in chemistry in 1985. He then joined GEC Hirst Research Centre in Wembley where he worked on semiconductor processing for three years, before returning to Bristol to study for a PhD in plasma etching of semi- conductors. His PhD was awarded in 1991, and he then remained at Bristol to co-found the CVD diamond research group.
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Gordon was afﬂicted with a number of medical problems beginning in childhood and continuing into the present that often disrupted what appeared to be an ideal life cheap mycelex-g 100 mg online antifungal amazon. As a young boy buy genuine mycelex-g on-line fungus or ringworm, Gordon was considered a “worrier” who had persist- ent stomachaches and headaches that resulted in daily visits to the school nurse buy generic mycelex-g 100 mg on-line antifungal cream for rash. She was very kind to Gordon since she knew he was the only child of a mother who was constantly in and out of the hospital with one med- ical problem or another. His father was sometimes given to bouts of “drink- ing and disappearing,” according to Gordon, who often had to take care of himself. In his teenaged years, Gordon suffered from asthma, which improved and disappeared when properly treated. That was important, because by then Gordon had become a real athlete and received pleasure and recogni- tion for his talents both as a soccer player in middle school and as a foot- ball champion in high school and college. After graduation, he maintained his athletic physique, regularly playing tennis, jogging, and lifting weights in the gym. As an adult, while he was outwardly a specimen of good health, he suf- fered quietly with serial illnesses, none of them of a truly serious nature, but all serious enough to adversely impact his life. He rarely slept well and in his twenties was diagnosed with ﬁbromyalgia. Apart from that, from time to time, he suffered from numerous gas- trointestinal issues, including peptic ulcers, irritable bowel syndrome, and continuous acid reﬂux (heartburn). Different doctors surmised different causes, such as food allergies, stress, and bacterial infections, for these med- ical phenomena. In his thirties, he presented with swollen glands, fever, body aches and chronic fatigue that lasted more Could Your Symptoms Be All (or Partly) in Your Mind? He was diagnosed with chronic fatigue syndrome (CFS) by his primary care physician, but another doctor declined to assign Gor- don this diagnosis as he didn’t meet all the documented criteria. Eventually, this condition dissipated, but he continued to suffer from occasional peri- ods of chronic dizziness and light-headedness. Although Gordon was functional, he often had to cancel appointments to meet clients and show them real estate, postpone vacations, or resched- ule dates all because of his physical ailments. He was labeled a hypochon- driac by some of his girlfriends, but the doctors would always ﬁnd a real medical problem. This was complicated by the fact that Gordon would eventually get better. Mysteriously, though, as one malady would get resolved, another would take its place. He rarely discussed his ailments with anyone because he didn’t want to lose clients or business, and most of all, he didn’t want anyone’s sympathy. Gordon did, however, blame his drinking problem on his continuing struggles with his illnesses. The burden of his constant doctor visits and deal- ing with chronic, albeit not life-threatening illnesses was eased, at least for a little while, when he was drinking. At one point, though, after ﬁnding himself in bed with yet another strange woman and a sexually transmitted disease (which fortunately was treatable), Gordon became concerned enough to seek help. He contacted a former drinking buddy who had joined Alcoholics Anonymous (AA) and been clean and sober for three years. Within a year of what he called the “pink cloud of recovery,” how- ever, Gordon began having recurrent nightmares. Along with the night- mares, a great deal of emotional pain bubbled to the surface, and he desperately wanted to start drinking again. The nightmares began to reveal to Gordon how he had repressed the memory of repeated sexual abuse inﬂicted by his father. Eventually, Gordon realized he needed professional help or he would relapse into drinking. He went into psychotherapy, and during this time, his variety of illnesses took a backseat. With great courage and emotional effort, Gordon recovered from his past traumas. He had grown 178 Diagnosing Your Mystery Malady into a kinder, gentler man who had been “healed. He returned to school, learned to be a massage therapist, and consequently changed professions. As he was strong and skilled at mas- sage, he quickly developed a following and became very successful. Within a short period of time, he met and married a wonderful woman and they had a baby boy. Life was good for Gordon until, at forty-seven, he developed yet another chronic and painful ailment, which he attributed to his work as a massage therapist. The intense low back pain and accompanying muscle spasms rendered him practically immobile. He had difﬁculty giving massages, began cancel- ing many appointments, and consulted a physical therapist. Finally, he consulted an orthopedic surgeon who, after x-rays and an MRI that revealed no physical impairment, suggested his patient look at what anxieties and repressed anger he might be experiencing that could be triggering his muscle spasms. At ﬁrst, Gordon was outraged at the suggestion that this was a psy- chological rather than a physical problem. This outrage quickly turned to depression because he truly believed he had “done his work” in therapy. After all, he no longer drank, he had healed from his traumatic childhood, he still attended AA meetings, and he was happy with his wife and child. He was convinced that this doctor was wrong; his symptoms had to be physical. He found a physician who was careful of Gordon’s addictive history and refused to give him painkillers. He prescribed nonsteroidal anti-inﬂammatories and gave Gordon an exercise regimen, which Gordon followed tenaciously. Gordon returned to the allergist who had prescribed medication to clear up his previous sinus infections and congestion. The medication helped; his sinus headaches ended but his asthma returned. At that point, aware of her husband’s history, Gordon’s wife suggested that he return to therapy. Were his physical symptoms a sign of repressed anger or some other deep-seated psychological need to cling to physical symptoms? Gordon sheepishly returned to the orthopedic surgeon to explore this issue further. The doctor suggested that Gordon use a modiﬁed version of the Eight Steps to Self-Diagnosis to answer that question. He was told to take as much time as he needed to complete these tasks because the doctor knew this might be a painful process. Gordon was told to modify this exercise to determine how many symptoms he had experienced during his lifetime and at what ages. He could get more speciﬁc, if neces- sary, once he and his doctor looked at the whole picture together.